Matsuda–Heck reaction with arenediazonium tosylates in water
نویسندگان
چکیده
منابع مشابه
Matsuda–Heck reaction with arenediazonium tosylates in water
An environmentally friendly Matsuda-Heck reaction with arenediazonium tosylates has been developed for the first time. A range of alkenes was arylated in good to quantitative yields in water. The reaction is significantly accelerated when carried out under microwave heating. The arylation of haloalkylacrylates with diazonium salts has been implemented for the first time.
متن کاملHeck reaction of arenediazonium salts with N,N-diprotected allylamines. Synthesis of cinnamylamines and indoles.
Novel palladium-catalyzed reactions of arenediazonium tetrafluoroborates with N,N-diprotected allylamines are presented. The reaction of arenediazonium tetrafluoroborates with N,N-(Boc)(2) allylamine allows for an easy approach to cinnamylamines whereas using 2-alkynyl-N-(allyl)trifluoroacetanilides and 2-iodo-N-(allyl)trifluoroacetanilide the reaction provides a useful tool for appending indol...
متن کاملNickel-catalysed cross-coupling reaction of aryl(trialkyl)silanes with aryl chlorides and tosylates.
Using highly stable, readily accessible, and recyclable 2-(2-hydroxyprop-2-yl)cyclohexyl-substituted arylsilanes activated by a mild carbonate base, nickel-catalysed silicon-based aryl-aryl cross-coupling reaction proceeds for the first time with inexpensive aryl chlorides and tosylates in a highly chemoselective manner.
متن کاملSandmeyer trifluoromethylation of arenediazonium tetrafluoroborates.
The development of methods for the introduction of trifluoromethyl groups into functionalized molecules is of great importance due to their presence in many top-selling pharmaceuticals, agrochemicals, and functional materials. Trifluoromethyl groups are known to impart desirable properties, such as higher metabolic stability, increased lipophilicity, and stronger dipole moments to druglike mole...
متن کاملIridium-Catalyzed ortho-Arylation of Benzoic Acids with Arenediazonium Salts.
In the presence of catalytic [{IrCp*Cl2 }2 ] and Ag2 CO3 , Li2 CO3 as the base, and acetone as the solvent, benzoic acids react with arenediazonium salts to give the corresponding diaryl-2-carboxylates under mild conditions. This C-H arylation process is generally applicable to diversely substituted substrates, ranging from extremely electron-rich to electron-poor derivatives. The carboxylate d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Beilstein Journal of Organic Chemistry
سال: 2015
ISSN: 1860-5397
DOI: 10.3762/bjoc.11.41